Saburo Saito Selected Research

Seasonal Allergic Rhinitis (Hay Fever)

1/2021	Long-term oral administration of transgenic rice containing cedar pollen T-cell epitopes potentially improves medication- and allergy-related quality-of-life scores.
1/2020	Safety and efficacy of rice seed-based oral allergy vaccine for Japanese cedar pollinosis in Japanese monkeys.
10/2019	T-cell activation by transgenic rice seeds expressing the genetically modified Japanese cedar pollen allergens.
1/2019	Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens.
7/2016	Cross-reactivity between major IgE core epitopes on Cry j 2 allergen of Japanese cedar pollen and relevant sequences on Cha o 2 allergen of Japanese cypress pollen.
7/2013	Analysis of conformational and sequential IgE epitopes on the major allergen Cry j 2 of Japanese cedar (Cryptomeria japonica) pollen in humans by using monoclonal antibodies for Cry j 2.
9/2005	Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine.

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Saburo Saito Research Topics

Disease

7	Seasonal Allergic Rhinitis (Hay Fever) 01/2021 - 09/2005
6	Hypersensitivity (Allergy) 01/2021 - 04/2006
6	Inflammation (Inflammations) 01/2021 - 03/2007
3	Pruritus (Itching) 01/2022 - 01/2017
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2007 - 01/2003
2	Retinal Degeneration 01/2021 - 10/2015
2	Atopic Dermatitis (Atopic Eczema) 01/2017 - 02/2002
2	Neoplasms (Cancer) 05/2010 - 05/2006
2	Autoimmune Diseases (Autoimmune Disease) 10/2009 - 03/2007
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2021
1	Pain (Aches) 01/2019
1	Infections 01/2011
1	Pinealoma (Pineoblastoma) 05/2010
1	Primitive Neuroectodermal Tumors (PNET) 05/2010
1	Medulloblastoma 05/2010
1	Uveitis 10/2009
1	Experimental Arthritis 04/2009
1	Arthritis (Polyarthritis) 04/2009
1	Wounds and Injuries (Trauma) 07/2008
1	Eosinophilia 01/2008
1	Respiratory Hypersensitivity 01/2008
1	Asthma (Bronchial Asthma) 01/2008
1	Airway Remodeling 01/2008
1	Atherosclerosis 03/2007
1	Coronary Artery Disease (Coronary Atherosclerosis) 03/2007
1	Disease Progression 04/2006
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 08/2002
1	Fibrosis (Cirrhosis) 08/2002
1	Necrosis 08/2002
1	Immediate Hypersensitivity 02/2002

Drug/Important Bio-Agent (IBA)

7	AllergensIBA 01/2021 - 02/2002
5	Immunoglobulin E (IgE)IBA 01/2020 - 02/2002
4	CytokinesIBA 01/2017 - 01/2008
2	Messenger RNA (mRNA)IBA 01/2022 - 04/2009
2	Retinaldehyde (Retinal)IBA 01/2021 - 10/2015
2	AntigensIBA 01/2019 - 04/2006
2	Indicators and Reagents (Reagents)IBA 01/2019 - 01/2007
2	EpitopesIBA 07/2016 - 07/2013
2	Peptides (Polypeptides)IBA 07/2013 - 04/2009
2	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2006 - 01/2003
1	AntipruriticsIBA 01/2022
1	Capsaicin (Zostrix)FDA Link 01/2022
1	Minocycline (Cyclops)FDA LinkGeneric 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	VaccinesIBA 01/2020
1	Analgesics (Analgesic Drugs)IBA 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 01/2019
1	c-Mer Tyrosine KinaseIBA 10/2015
1	Monoclonal AntibodiesIBA 07/2013
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 07/2013
1	Thymic Stromal LymphopoietinIBA 01/2012
1	Picryl Chloride (Trinitrochlorobenzene)IBA 01/2012
1	Xylenes (Xylene)IBA 01/2012
1	tau Proteins (tau Protein)IBA 05/2010
1	SynaptophysinIBA 05/2010
1	Tumor Biomarkers (Tumor Markers)IBA 05/2010
1	Phosphopyruvate Hydratase (Enolase)IBA 05/2010
1	TubulinIBA 05/2010
1	Acetylserotonin O-Methyltransferase (Hydroxyindole O Methyltransferase)IBA 05/2010
1	Serotonin (5 Hydroxytryptamine)IBA 05/2010
1	Rhodopsin (Visual Purple)IBA 05/2010
1	ArrestinIBA 05/2010
1	EnzymesIBA 05/2010
1	ChromograninsIBA 05/2010
1	Neurofilament ProteinsIBA 05/2010
1	SuperantigensIBA 10/2009
1	Collagen Type II (Type II Collagen)IBA 04/2009
1	Fluticasone (Cutivate)FDA LinkGeneric 01/2008
1	CholesterolIBA 03/2007
1	Immunomodulating AgentsIBA 03/2007
1	Coenzyme A (CoA)IBA 03/2007
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 03/2007
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2007
1	Proteins (Proteins, Gene)FDA Link 05/2006
1	Rod OpsinsIBA 04/2006
1	Glial Fibrillary Acidic ProteinIBA 04/2006
1	Protein Subunit VaccinesIBA 09/2005
1	AlbuminsIBA 08/2002
1	Ethanol (Ethyl Alcohol)IBA 08/2002

Therapy/Procedure

3	Immunotherapy 01/2020 - 09/2005
2	Oral Administration 01/2021 - 09/2005